01
Protein–Ligand Interaction
Detailed binding analysis, computational docking, and molecular modeling to characterize and optimize affinity.
Now accepting Q3 engagements
Precision protein science for the next generation of therapies.
ProLigand Nexus partners with biotech and pharma teams to accelerate drug discovery — from target characterization to lead optimization — with rigorous, publication-grade science.
PDB · Active site
Ligand bound, ΔG = −9.4 kcal/mol
Structural Biology◆Cryo-EM◆NMR◆X-Ray Crystallography◆Molecular Dynamics◆Fragment-Based Discovery◆Biophysics◆SPR · ITC · DSF◆Structural Biology◆Cryo-EM◆NMR◆X-Ray Crystallography◆Molecular Dynamics◆Fragment-Based Discovery◆Biophysics◆SPR · ITC · DSF◆Structural Biology◆Cryo-EM◆NMR◆X-Ray Crystallography◆Molecular Dynamics◆Fragment-Based Discovery◆Biophysics◆SPR · ITC · DSF◆
Founder
Dr. F. Ben Bdira
Mission & Vision
Bridging academic rigor with the pace of industrial discovery.
We help biotech and pharmaceutical companies translate structural insight into actionable chemistry. Every engagement is led personally — no handoffs, no junior teams — combining two decades of protein science with a clear focus on what advances your pipeline.
- Hands-on senior scientist on every project
- Transparent milestones and weekly progress notes
- Publication-grade data, IP-clean deliverables
Core Services
Specialized consulting across every stage of drug discovery.
Engage us for a focused sprint or as an embedded scientific partner — scoped to fit your stage and runway.
02
High-Throughput Screening
Custom assay development including fluorescence, ELISA and biophysical approaches tailored to your target.
03
Protein Engineering
Enzyme engineering, expression, purification and functional characterization for therapeutic and industrial use.
04
Molecular Modeling
Structural analysis with state-of-the-art simulation, MD and structure prediction tools.
05
Project Guidance
Strategic R&D management and mentorship for research teams navigating early discovery to lead optimization.
06
Assay Optimization
Robust, reproducible workflows — from feasibility to scale — designed to de-risk decision-making.
How We Work
A four-step protocol built for momentum.
- 01Discover
Scoping call to map the scientific question, constraints and decision points.
- 02Design
A tailored plan — methods, milestones, deliverables and a fixed timeline.
- 03Deliver
Hands-on execution with weekly updates and full data transparency.
- 04Decide
Clear, actionable recommendations to advance — or pivot — your program.
Let's collaborate
Have a target in mind? Let's talk.
Whether you're validating a new modality or de-risking a clinical candidate, a 30-minute conversation is the fastest way to know if we're the right partner.
Email Dr. Ben Bdira- fredjbdira@gmail.com
- Phone
- +31 6 16 840 760
- Location
- Bioscience Park, 2332EA Leiden, NL